Human GM-CSF (AF)

GM-CSF a hematopoietic growth factor plays a role in stimulating the development of neutrophils and macrophages while also supporting the proliferation and maturation of early erythroid megakaryocytic and eosinophilic progenitor cells. It's primarily produced in endothelial cells monocytes fibroblasts and T-lymphocytes. GM-CSF has the additional effect of inhibiting neutrophil migration and boosting the functional activity of mature end cells. Unlike G-CSF GM-CSF molecules are species-specific with no cross-reactivity between Human and murine versions. Recombinant Human GM-CSF is a 14.6 kDa globular protein comprising 128 amino acids featuring two intramolecular disulfide bonds and two potential N-linked glycosylation sites.

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Regenerative Medicine

Stem Cell Research

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