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Cellartis® MSC EV Wonder

We are delighted to announce an exciting new partnership between TCS Biosciences and Takara Bio, bringing the renowned Cellartis® portfolio directly to researchers across the United Kingdom.

This collaboration strengthens our growing life science offering and provides UK scientists with easier access to Takara Bio's trusted stem cell technologies, supported by the dedicated service and technical expertise you expect from TCS Biosciences.

Cellartis MSC EV Wonder is a chemically defined, xeno-free medium optimized for robust, consistent production of mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs). It enables a seamless transition from expansion to production with no adaptation needed. This medium delivers high EV yields, low background particles, strong CD9/CD81/CD63 expression, and defined particle size for high-performance EVs.

The MSC EV Wonder system consists of two chemically defined components: a basal medium and an EV-specific supplement. Together, they form a complete, optimized solution for high-yield EV production in a streamlined format.

This medium is built to consistently deliver high EV output with excellent purity, helping you achieve more reliable and reproducible results. Its clean formulation supports easy downstream processing and reduces background interference. MSC EV Wonder is an ideal choice for researchers looking to efficiently produce high-quality MSC-derived EVs for advanced research and translational development.

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Cellartis MSC EV Wonder

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Overview

High-performance medium for MSC-derived EV production that is engineered for consistency, safety, and yield—Cellartis MSC EV Wonder empowers scalable, clinically relevant EV manufacturing. Whether for advanced research or translational workflows, Cellartis MSC EV Wonder delivers results you can trust.

Chemically defined xeno-free formulation - ensures consistent results
Phenol red-free - enables easy downstream EV analysis
Seamless expansion to production - eliminates the need for additional optimization
High EV yield - maximizes EV output
Multi-source MSC support - demonstrates high performance with MSCs derived from bone marrow, adipose tissues, and umbilical cords
Low particle background - delivers cleaner isolations with reduced interference

Easy-to-follow workflow for efficient MSC-derived EV production. Minimize variability and streamline your EV workflow with a simple two-phase process using Cellartis MSC Xeno-Free Culture Medium (Cat. # Z-CELL-Y50200) for MSC expansion and Cellartis MSC EV Wonder (Cat. # Z-CELL-Y51000) for EV production.

Applications

MSC-derived EVs are widely studied for their regenerative, immunomodulatory, and therapeutic delivery properties. Their natural bioactivity and safety profile make them valuable in both academic research and early-stage clinical development, particularly in the following areas:

Regenerative medicine studies, including tissue repair and wound healing
Cell-free therapy development using MSC-derived EVs
EV-based drug delivery research, leveraging MSC-derived EVs as natural carriers
Immunomodulatory research for autoimmune and inflammatory diseases
Neurodegenerative disease models, including stroke, ALS, and Parkinson’s
Cardiovascular disease models exploring the protective effects of MSC-derived EVs
Oncology research for tumor modulation and drug resistance studies
Liver disease and fibrosis research using MSC-derived EV signaling
Acute kidney injury and other organ protection studies
Graft-versus-host disease (GVHD) models in transplantation research

Additional Information

Please refer to the product's Certificate of Analysis for detailed information on storage conditions, product components, and technical specifications. To view the contents of a kit, please consult the Kit Components List. Both documents can be found under the Documents tab on the Takara website, available here: https://www.takarabio.com/products/stem-cell-research