Murine NOGGIN

Product Code: ZRP-MNOGN-5UG

CI ID: 6874

Pack Size: 5ug

£65.00

More Details

Recombinant Murine Noggin is a high-purity, animal-free recombinant protein expressed to mimic the biological activity of native mouse Noggin, a secreted antagonist of bone morphogenetic proteins (BMPs). Noggin plays a critical role in embryonic development and tissue patterning by binding BMPs and preventing receptor interaction, making it an essential tool for stem cell research, developmental biology, and regenerative medicine studies.

Specification

Species	Mouse
Published species	Mouse
Expression System	E. coli
Amino acid sequence	MQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGPAG GAEDLAELDQ LLRQRPSGAM PSEIKGLEFS EGLAQGKKQR LSKKLRRKLQ MWLWSQTFCP VLYAWNDLGS RFWPRYVKVG SCFSKRSCSV PEGMVCKPSK SVHLTVLRWR CQRRGGQRCG WIPIQYPIIS ECKCSC
Molecular weight	46.4 kDa
Class	Recombinant
Type	Protein
Purity	≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration	<0.1 EU/µg
Activity	Determined by its ability to inhibit 10.0 ng/ml of BMP-4 induced alkaline phosphatase production by ATDC5 chondrogenic cells. The expected ED50 for this effect is 2.9 - 4.3 ng/ml of Noggin.
Conjugate	Unconjugated
Form	Lyophilized
Contains	no preservative
Storage conditions	-20°C