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EliGene<sup>®</sup> Ureaplasma UNI Kit

EliGene® Ureaplasma UNI Kit

Pack Size: 50 reactions

Product Code: Z10-90049-UNI

Compatible Instruments: UNI Kit is intended for ABI7500FAST, SmartCycler, RotorGene 6000 and for all LightCycler®instruments.

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Note: Euro Equivalents shown for information only.

Clinical study description and results: Within the frame of testing the functional characteristics of EliGene® Ureaplasma LC Kit, in total 57 clinical specimens (urine, swabs) were analysed. The EliGene® Ureaplasma LC Kit diagnosed correctly 9 specimens as Ureaplasma urealyticum or Ureaplasma parvum positive. In total 48 specimens were rightly determined by EliGene® Ureaplasma LC Kit as Ureaplasma urealyticum or Ureaplasma parvum negative. Sensitivity: 100%, Specificity: 100%.

Pathogen description: Ureaplasma urealyticum is bacterium belonging to the family Mycoplasmataceae. U. urealyticum consists of 14 serovars that can be divided into two biovars, biovars 1 and biovars 2, on the basis of genotypic characteristics. Evidence has been presented that the species is currently known as U. urealyticum should be separated into two species, namely U. parvum (previously U. urealyticum biovar 1) and U. urealyticum (previously, U. urealyticum biovar 2). The majority of human Ureaplasma isolates belong to the new species U. parvum, Ureaplasma sp. is the main cause of non-gonococcal, non-chlamydial urethritis, acute prostatitis and acquired arthritis in me. In pregnant and non-pregnant women, Ureaplasma can cause chorioamnionitis and pre-term delivery, abortion, pre-term birth, vaginitis and cervicities. Clinical studies have demonstrated that infants born to infected mothers become infected with these bacteria, and colonization of the respiratory tract of infants has been associated with pneumonia, respiratory tract of infants has been associated with pneumonia, respiratory distress and meningitis.

References: Allam AB, Alvarez S, Brown MB, Reyes L. 2011. Ureaplasma parvum infection alters filamin A dynamics in host cells. BMC Infect Dis. 11:101. Pinna GS, Skevaki CL, Kafetzis DA. 2006. The significance of Ureaplasma urealyticum as a pathogenic agent in the paediatric population. Curr Opin infect Dis. 19(3):283-9.

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t: +44 (0)1296 714222
f: +44 (0)1296 714806

Botolph Claydon, Buckingham, MK18 2LR, United Kingdom

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TCS Biosciences Ltd
t: +44 (0)1296 714222  •  f: +44 (0)1296 714806  •  e:
Botolph Claydon, Buckingham, MK18 2LR, United Kingdom

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