Human TGF-b3 (AF)

The three mammalian isoforms of TGF-?, namely TGF-?1, ?2, and ?3, activate the same receptor and provoke similar biological responses. These versatile cytokines oversee cell proliferation, growth, differentiation, and motility, along with orchestrating the synthesis and placement of the extracellular matrix. They play vital roles in various physiological activities like embryogenesis, tissue restructuring, and wound healing. Typically, they are secreted in latent complexes, stored at cell surfaces and within the extracellular matrix.

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