Human GDNF (AF)

GDNF is a homodimeric neurotrophic factor connected by disulfide bonds, sharing structural similarities with Artemin, Neurturin, and Persephin. These proteins are part of the cysteine-knot superfamily of growth factors, known for their stable dimeric structures. GDNF transmits signals through a complex receptor system involving RET and one of four GFR? receptors (?1-?4). Its specific actions include enhancing dopamine uptake and promoting the survival and morphological development of midbrain neurons.

Biomanufacturing

Research

Regenerative Medicine

Stem Cell Research

Tissue Engineering

View Products by Applications