Human BMP-4 (AF)

Bone morphogenetic proteins (BMPs) belong to the TGF-β superfamily, a group of structurally related signaling proteins. This superfamily is widely distributed in the body and plays diverse roles during prenatal and postnatal life. Like BMP-7, BMP-4 contributes significantly to bone and cartilage development and maintenance. Reduced BMP-4 expression is linked to various bone disorders, including Fibrodysplasia Ossificans Progressiva, an inherited condition.

Product Specifications
Species	Human, Mouse, Rat
Published species	Amphibian, Chicken, Human, Mouse, Non-human primate, Rat
Expression System	E. coli
Amino acid sequence	MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
Molecular weight	27.0 kDa
Class	Recombinant
Type	Protein
Purity	? 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration	<0.1 EU/µg
Activity	Bio-Assay using C6 cells. The ED50 was determined to be ? 2.0 ng/ml, corresponding to a specific activity of ? 5.0 x 10^5 units/mg.
Conjugate	Unconjugated
Form	Lyophilized
Contains	no preservative
Storage conditions	-20°C

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Regenerative Medicine

Stem Cell Research

Tissue Engineering

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