Human IL-2 (AF)

IL-2 stands out as a potent immunoregulatory lymphokine generated by T cells following antigenic or mitogenic stimulation. Its signaling through IL-2R is critical for T cell proliferation and other vital immune response activities. IL-2 plays a pivotal role in stimulating the growth and differentiation of various immune cells like B cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages, and oligodendrocytes. The recombinant Human IL-2 is a 15.5 kDa protein composed of 134 amino acid residues, featuring one intrachain disulfide bond.

Species	Human
Published species	Bovine, Human, Mouse
Expression System	E. coli
Amino acid sequence	MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFAQSII STLT
Molecular weight	15.5 kDa
Class	Recombinant
Type	Protein
Purity	≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration	<0.1 EU/µg
Activity	The ED50 was determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^7 units/mg.
Conjugate	Unconjugated
Form	Lyophilised
Contains	no preservative
Storage conditions	-20°C

CAUTION

For Research Use Only. Not for use in diagnostic procedures.

Biomanufacturing

Research

Regenerative Medicine

Stem Cell Research

Tissue Engineering

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