Human FGF-basic (154 a.a.) (AF)

FGF-basic, a member of the FGF family comprising 23 known proteins, plays a pivotal role in prenatal development, postnatal growth, and tissue regeneration. It facilitates cellular proliferation and differentiation in various tissues. This growth factor is non-glycosylated and binds to heparin, and it is expressed in multiple organs and cell types including the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells, and endothelial cells. FGF-basic communicates through several receptors including FGFR 1b, 1c, 2c, 3c, and 4. Recombinant Human FGF-basic is a 17.2 kDa protein composed of 154 amino acid residues.

Species	Human
Published species	Amphibian, Bovine, Chicken, Dog, Hamster, Horse, Human, Mouse, Non-human primate, Rabbit, Rat, Virus, Zebrafish
Expression System	E. coli
Amino acid sequence	AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS
Molecular weight	17.2 kDa
Class	Recombinant
Type	Protein
Purity	≥ 95% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration	<0.1 EU/µg
Activity	Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^7 units/mg.
Conjugate	Unconjugated
Form	Lyophilised
Contains	no preservative
Storage conditions	-20°C

CAUTION

For Research Use Only. Not for use in diagnostic procedures.

Biomanufacturing

Research

Regenerative Medicine

Stem Cell Research

Tissue Engineering

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