Human IL-7 (Animal-Free Recombinant)

IL-7 is a hematopoietic growth factor with a key impact on early B and T cells. It originates from thymic stromal cells, spleen cells, and keratinocytes. In addition to its primary effects, IL-7 can collaborate with other factors like ConA and IL-2 to stimulate the proliferation of mature T cells. Interestingly, Human and murine IL-7 show cross-species reactivity. Recombinant Human IL-7 is a 17.5 kDa protein comprising 153 amino acid residues.

Species	Human
Published species	Hamster, Human, Mouse, Rabbit, Virus
Expression System	E. coli
Amino acid sequence	MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH
Molecular weight	17.5 kDa
Class	Recombinant
Type	Protein
Purity	≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration	<0.1 EU/µg
Activity	Determined by its ability to stimulate the proliferation of mouse 2E8 cells. The expected ED50 ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10^6 units/mg.
Conjugate	Unconjugated
Form	Lyophilised
Contains	no preservative
Storage conditions	-20°C

CAUTION

For Research Use Only. Not for use in diagnostic procedures.